pH-Dependent Conformational Changes of Concanavalin A
نویسندگان
چکیده
منابع مشابه
Characterizing a histidine switch controlling pH-dependent conformational changes of the influenza virus hemagglutinin.
During the fusion of the influenza virus to the host cell, bending of the HA2 chain of hemagglutinin into a hairpin-shaped structure in a pH-dependent manner facilitates the fusion of the viral envelope and the endosomal membrane. To characterize the structural and dynamical responses of the hinge region of HA2 to pH changes and examine the role of a conserved histidine in this region (the hing...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1971
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.68.9.2173